Education and Research Experience
2003 - 2007 B.S. College of Chemistry, Beijing Normal University, China
2008 - 2014 Ph.D. Institute of Chemistry, Chinese Academy of Sciences (CAS), China (Supervisor: Prof. Mei-Xiang Wang)
2014 - 2019 Assistant Professor, Institute of Chemistry, Chinese Academy of Sciences (CAS), China
2019 - now Associate Professor, Institute of Chemistry, Chinese Academy of Sciences (CAS), China
2021 - 2022 Visiting Scientist, Greifswald University, Germany. (Prof. Uwe T. Bornscheuer's Group)
CAS Key Laboratory of Molecular Recognition and Function
Institute of Chemistry, Chinese Academy of Sciences
Address: Zhongguancun North First Street 2,100190 Beijing, China
ORCID number: 0000-0002-9415-2181
Yu-Fei Ao,* Hui-Juan Hu, Cheng-Xin Zhao, Peng Chen, Tingting Huang, Hui Chen,* Qi-Qiang Wang, De-Xian Wang, Mei-Xiang Wang, "Reversal and amplification of the enantioselectivity of biocatalytic desymmetrization toward meso heterocyclic dicarboxamides enabled by rational engineering of amidase", ACS Catal. 2021, 11, 6900-6907.
Peng-Wei Xu, Xiao-Yuan Cui, Chen Chen, Feng Zhou, Jin-Sheng Yu, Yu-Fei Ao,* Jian Zhou,* "Enantioselective synthesis of Cα‑ tetrasubstituted N‑hydroxyl-α-amino nitriles via cyanation of ketonitrones using Me2(CH2Cl)SiCN", Org. Lett. 2021, 23, 8471-8476.
Hui-Juan Hu, Qi-Qiang Wang, De-Xian Wang, Yu-Fei Ao,* "Modification of the enantioselectivity of biocatalytic meso-desymmetrization for synthesis of both enantiomers of cis-1,2-disubstituted cyclohexane by Amidase engineering", Adv. Synth. Catal. 2021, 363, 4538-4543.
Hui-Juan Hu, Qi-Qiang Wang, De-Xian Wang, Yu-Fei Ao,* "Enantioselective biocatalytic desymmetrization for synthesis of enantiopure cis-3,4-disubstituted pyrrolidines", Green Synth. Catal. 2021, 2, 324-327.